Pathology MCQ 152

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Primary IgA nephropathy is believed to result from which immunopathogenetic mechanism?

  1. Deposition of immune complexes containing IgA1 in mesangium with activation of alternative complement pathway

  2. Defective hepatic clearance of immune complexes containing IgA

  3. Increased mucosal synthesis of IgA that cross reacts with mesangial antigens

  4. monoclonal B cell proliferation producing mesangiopathic IgA

  5. planted viral antigens in mesangium inducing an autoimmune response

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Category: Pathology MCQs



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