MCQ Pharmacology Answer 3

on with 0 comments

The correct answer is E

Phenytoin is approximately 90 per cent bound to serum albumin. Therefore, in an initial total plasma phenytoin concentration of 20ìg/ml represents the sum of the protein bound drug (90 per cent of 20 = 18ìg/ml) and the unbound drug (10 per cent of 20 = 2ìg/ml). The unbound drug is available for distribution to the site of therapeutic effect (ie, the brain), peripheral tissues, and the site of elimination (the liver). The bound drug is confined to the bloodstream.

Category: Pharmacology MCQs



Post a Comment

Is there something you wish to add? Have something to say? Feel free to leave a comment.